Inflammation

Psoriasis Model

Epistem offers a clinically relevant in vitro psoriasis model. Psoriasis is a common inflammatory disorder affecting the skin, characterised by inflamed and itchy plaques. An appropriate in vivo system for testing psoriasis novel therapeutic agents is lacking.

Psoriasis Model Description

Human primary keratinocytes are stimulated with a cocktail of pro-inflammatory cytokines to induce a gene expression profile which mimics that of psoriasis patients. The effects on gene expression in response to novel therapeutic agents can be assessed.

Readouts

  • Gene Expression
  • Protein Expression

Illustration of the effects of psoriasis

Illustration of the effects of psoriasis

© 2013-17 Epistem Ltd. : : last modified: 10 May 2016

Epistem Ltd is a division of genedrive plc