Analytical Services

Histology

Epistem can undertake work from any stage in the histological process, from initial fixation and tissue receipt, to digital scanning, and analysis of externally stained slides. Epistem provides appropriate fixation details for specific morphological target preservation, tissue processing, OCT and paraffin wax embedding and orientation of tissue and sectioning. High quality digital image capture and reporting is available as required along with full qualitative and quantitative image analysis.

Features of Epistem's Histology Service:

  • Tissue sourcing / tissue provision
  • De-calcification of ossified tissue prior to processing
  • Trimming or bundling as required
  • Programmable automated tissue processor with vacuum wax infiltration and 240 cassette run capacity
  • Embedding of cells or tissues into paraffin or OCT
  • Ability to provide serial or step sections
  • Automated H&E Autostainer. Programmes can be tailored to the H&E preference of the customer
  • Cryosectioning
  • Tinctorial and special staining
  • Laboratory facilities in both the UK and US 

Epistem offers a wide range of special stains including:

  • Masson's Trichrome
  • Acidified Toluidine Blue
  • Periodic acid Schiff (PAS)
  • Grünwald Giemsa
  • Masson Fontana Silver
  • Van Gieson's
  • Gomori's Aldehyde Fuchsin
  • MSB Fibrin
  • Gordon and Sweets
  • Others on request

Massom Trichome staining for collagen & muscle fibres in human skin

Masson's trichrome staining for collagen & muscle fibres in human skin

Van Gieson's staining for collagen & connective tissue in tongue

Van Gieson's staining for collagen & connective tissue in tongue

Orcein staining for elastic fibres in human skin

Orcein staining for elastic fibres in human skin

© 2013-17 Epistem Ltd. : : last modified: 14 Mar 2014

Epistem Ltd is a division of genedrive plc